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Bayer's CONTOUR And Bayer's BREEZE2 Blood Glucose Monitoring Systems Do Not Use Problematic GDH-PQQ Technology
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| The U. S. Food and Drug Administration issued Advice for Diabetic Patients and their Caregivers on August 13, stating that blood glucose meters that use GDH-PQQ technology may "produce a falsely high (elevated) blood glucose result." Since 2006, Bayer Diabetes Care has not distributed test strips that use GDH-PQQ (glucose dehydrogenase pyrroloquinoline quinone) glucose monitoring technology for its blood glucose meters.
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| 8/15/2009
1:00 AM |
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Bayer Statement On U.S. Food And Drug Administration Advice For Patients: Serious Errors With Certain Blood Glucose Monitoring Test Strips
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| Since 2006, Bayer Diabetes Care has not distributed test strips that use GDH-PQQ (glucose dehydrogenase pyrroloquinoline quinone) glucose monitoring technology for its blood glucose meters. As referenced in a U.S. Food and Drug Administration Advice for Diabetic Patients and their Caregivers issued today, blood glucose meters that use GDH-PQQ technology may "produce a falsely high (elevated) blood glucose result.
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| 8/15/2009
1:00 AM |
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Tool Finds Best Heart Disease, Stroke Treatments For Patients With Diabetes
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| Researchers from North Carolina State University and Mayo Clinic have developed a computer model that medical doctors can use to determine the best time to begin using statin therapy in diabetes patients to help prevent heart disease and stroke. "The research is significant because patients with diabetes are at high risk for cardiovascular disease and statins are the single most commonly used treatment for patients at risk of heart disease and/or stroke," says Dr.
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| 8/15/2009
1:00 AM |
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Even At Advanced Age, Exercise Boosts Muscle Cells' Energy Centers
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| Whether a person is 8 years old or 88, exercise helps protect against type 2 diabetes. It does this, in part, by revving up the function of small structures called mitochondria, which are found inside cells. Diabetes specialist Nicolas Musi, M.D., associate professor in the School of Medicine at The University of Texas Health Science Center at San Antonio, is studying the effects of exercise on 100 muscle biopsy specimens and is documenting how exercise affects the mitochondria.
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| 8/15/2009
1:00 AM |
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More Fruits And Veggies, Less Salt Prevent Kidney Stones From Forming
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| Researchers have found another reason to eat well: a healthy diet helps prevent kidney stones. Loading up on fruits, vegetables, nuts, low-fat dairy products, and whole grains, while limiting salt, red and processed meats, and sweetened beverages is an effective way to ward off kidney stones, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).
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| 8/15/2009
12:00 AM |
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Tissue Scarring Key To Link Between Obesity And Diabetes
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| The team, in collaboration with University Hospital Aintree, the University of Warwick and researchers in Sweden, found that people classified as obese and those with pre-diabetes have raised levels of a protein called SPARC, that can cause tissue scarring.
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| 8/15/2009
12:00 AM |
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Primary Care Needs Of Those Living With HIV Highlighted By Updated Guidelines
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| With HIV patients living longer thanks to advances in treatment, the primary care needs of those living with HIV have never been more important. Updated, evidence-based guidelines from the HIV Medicine Association (HIVMA) and the Infectious Diseases Society of America (IDSA) are designed to help providers manage the care of those living with this complex chronic infection.
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| 8/15/2009
12:00 AM |
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Supporting Research On Age-Related Diseases And Clinical Care
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| The American Federation for Aging Research (AFAR), The National Institute on Aging (NIA), The Atlantic Philanthropies, The John A. Hartford Foundation, The Starr Foundation and other program partners are pleased to announce the 2009 recipients of the Paul B. Beeson Career Development Awards in Aging Research Program.
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| 8/14/2009
12:00 AM |
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Treating High Systolic Blood Pressure In Non-Diabetic Patients Could Be Beneficial
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| Treatment to lower high systolic blood pressure in non-diabetic patients is associated with a reduction in left ventricular hypertrophy (LVH), a thickening of the heart muscle that can lead to heart failure and rhythm problems. Thus, a lowering of systolic blood pressure targets from the currently recommended 140 mm/Hg or less to below 130 mm Hg should be the treatment goal in low-risk patients with high blood pressure, concludes an Article published in this week's edition of The Lancet.
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| 8/14/2009
12:00 AM |
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Glucose Intolerance In Animals Reversed By Carnitine Supplements
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| Supplementing obese rats with the nutrient carnitine helps the animals to clear the extra sugar in their blood, something they had trouble doing on their own, researchers at Duke University Medical Center report. A team led by Deborah Muoio (Moo-ee-oo), Ph.D., of the Duke Sarah W.
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| 8/13/2009
2:00 AM |
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Radiation Therapy May Increase Diabetes Risk In Childhood Cancer Survivors
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| Childhood cancer survivors treated with total body or abdominal radiation may have an increased risk of diabetes, according to a report in the August 10/24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. This correlation does not appear to be related to patients' body mass index or physical inactivity.
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| 8/12/2009
3:00 PM |
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Enzyme Discovery May Lead To Powerful New Therapy For Asthma
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| University of Texas Medical Branch at Galveston researchers have found that a single enzyme is apparently critical to most allergen-provoked asthma attacks - and that activity of the enzyme, known as aldose reductase, can be significantly reduced by compounds that have already undergone clinical trials as treatments for complications of diabetes.
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| 8/12/2009
2:00 AM |
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TAU's Easy-To-Swallow Drug Restores Autoimmune Function In Diabetics
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| Found in 30% of all human cancer tumors, the Ras protein literally "drives cells crazy," says Prof. Yoel Kloog, the dean of the Faculty of Life Sciences at Tel Aviv University. Prof. Kloog was the first in the world to develop an effective anti-Ras drug against pancreatic cancer, currently in clinical trials. Now, new research published in the June issue of the European Journal of Pharmacology shows that the drug might be able to slow the progression of diabetes as well.
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| 8/12/2009
12:00 AM |
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Stimulus Funding Helps K-State Biochemist Study Eye's Lens In Diabetes, Galactosemia Patients
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| Thanks to a grant awarded through federal stimulus research funding, a Kansas State University biochemist has more funding for research that could eventually help diabetics preserve their eyesight. Dolores Takemoto, a K-State professor of biochemistry, received more than $366,000 from the National Eye Institute to study how a particular enzyme affects the lens.
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| 8/12/2009
12:00 AM |
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Myths About Insulin
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| People diagnosed with type 2 diabetes often resist taking insulin because they fear gaining weight, developing low blood sugar and seeing their quality of life decline. A study recently completed at UT Southwestern Medical Center suggests that those fears are largely unfounded and that patients and physicians should consider insulin as a front-line defense, as opposed to a treatment of last resort for non-insulin-dependent diabetes.
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| 8/12/2009
12:00 AM |
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Reducing Cardiovascular Events: International Insulin Drug Trial
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| Accumulating safety data from the large, international ORIGIN trial have been reviewed by its independent data monitoring committee, who have concluded that there is no cause for concern. This six-year study, which is lead by McMaster University professors Dr. Hertzel Gerstein and Dr.
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| 8/12/2009
12:00 AM |
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Array BioPharma Reports Positive Results Of Its Oral Glucokinase Activator In Type 2 Diabetes Patients
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| Array BioPharma Inc. announced yesterday positive top-line data from a Phase 1 clinical trial in patients with Type 2 diabetes with its novel small molecule glucokinase activator (GKA), ARRY-403. The drug met its primary and secondary endpoints of safety, pharmacokinetics and glucose control. ARRY-403 was evaluated in a Phase 1 single ascending dose study.
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| 8/11/2009
10:00 PM |
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Discovery Of A Gene That May Play A Role In Type 1 Diabetes
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| Scientists at Stanford University have identified a gene that may play a role in the development of type 1 diabetes, an autoimmune disease in which the immune system attacks the body's insulin-producing cells. Insulin, a hormone produced by cells of the pancreas, helps the body to absorb sugars found in food and to maintain blood sugar at appropriate levels. The study team, led by C. Garrison Fathman, M.D., examined genes from mice that develop a type 1 diabetes-like disease. Dr.
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| 8/11/2009
5:00 AM |
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Diabetes Risk May Be Increased By Insufficient Sleep
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| Short sleep times, experienced by many individuals in Westernized societies, may contribute to the development of insulin resistance and reduced glucose tolerance, which in turn may increase the long-term risk of diabetes, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
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| 8/11/2009
5:00 AM |
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Joslin Study Identifies Gene Linked To Rare Form Of Diabetes
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| Researchers at the Joslin Diabetes Center have linked another gene to a rare form of diabetes, a finding that could prove beneficial to those with the more common type 2 diabetes. In a study published this week in Proceedings of the National Academy of Sciences Early Edition, a team led by Alessandro Doria, M.D., Ph.D. and Rohit N. Kulkarni, M.D., Ph.D.
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| 8/11/2009
12:00 AM |
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Converting Noninsulin-Producing Alpha Cells In The Pancreas To Insulin-Producing Beta Cells
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| In findings that add to the prospects of regenerating insulin-producing cells in people with type 1 diabetes, researchers in Europe -- co-funded by the Juvenile Diabetes Research Foundation -- have shown that insulin-producing beta cells can be derived from non-insulin-producing cells in the pancreas.
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| 8/8/2009
12:00 AM |
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More Insulin-Producing Cells, At The Flip Of A 'Switch'
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| Researchers have found a way in mice to convert another type of pancreas cell into the critical insulin-producing beta cells that are lost in those with type I diabetes. The secret ingredient is a single transcription factor, according to the report in the August 7th issue of Cell, a Cell Press journal. When the gene called Pax4 is forced on in pancreatic alpha cells, the cells change their identity to become beta cells, the researchers found.
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| 8/8/2009
12:00 AM |
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Colon Cancer May Yield To Cellular Sugar Starvation
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| Scientists at the Johns Hopkins Kimmel Cancer Center have discovered how two cancer-promoting genes enhance a tumor's capacity to grow and survive under conditions where normal cells die. The knowledge, they say, may offer new treatments that starve cancer cells of a key nutrient - sugar. However, the scientists caution that research does not suggest that altering dietary sugar will make any difference in the growth and development of cancer.
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| 8/7/2009
1:00 AM |
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Innovative Diabetes Drug Discovery And Development Partnership Announced By JDRF And GNF
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| The Juvenile Diabetes Research Foundation has said that it has entered into a novel collaborative research agreement with the Genomics Institute of the Novartis Research Foundation (GNF) to create a diabetes drug discovery and development platform. The four-year program is one of the largest and most comprehensive collaborations in the 40 year history of JDRF, a leader in setting the agenda for diabetes research worldwide and the largest charitable funder and advocate of type 1 research.
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| 8/7/2009
12:00 AM |
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UCLA Welcomes Startup To New Incubator Space At California NanoSystems Institute
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| UCLA's newly launched on-campus technology incubator at the California NanoSystems Institute (CNSI) has opened lab space to MediSens Wireless, a startup company that develops and manufactures personal body-monitoring systems for medical and health applications. The incubator program was established in March to nurture early-stage research and accelerate the commercial translation of technologies developed at UCLA.
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| 8/7/2009
12:00 AM |
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